I've found a reduction in gravity works best. Less oxygen is required for more work when growth occurs in negative Gs, as well as less structural support.
What no one in the scientific community wants to address is that the earth's gravity has increased over time. The giant insects and animals of millions of years ago could not exist under current gravitational conditions. You can't have a dragonfly with 30" wingspan today no matter how much oxygen you supply, and if you did it won't be able to fly. Neither could a 244 lb
Argentavis magnificens with a 28' wingspan. Forget about a 550lb
Quetzalcoatlus with 52' wingspan!
Dinosaurs could never support their weight under current conditions. That's why the larges animal today, the blue whale, can only exist with the help of water to support its bulk. A 100+ ton, 120' long
Argentinosaurus wouldn't even be able to lift its head today.
Because of this I've only succeeded producing giant mantids (up to 6') in low earth orbit and then only because acceleration of gravity is cancelled by the centrifugal acceleration induced by the orbital speed. Unfortunately, the cost of maintaining Low Earth Orbit Station Precarious is exorbitant and my creatures cannot survive on the surface so only I get to enjoy them, but let me tell you, escaping a 6' mantid in zero G is not very enjoyable!